Fungicidal Monoclonal Antibody C7 Binds to Candida albicans Als3
نویسندگان
چکیده
منابع مشابه
Fungicidal monoclonal antibody C7 interferes with iron acquisition in Candida albicans.
We have developed a monoclonal antibody (MAb), C7, that reacts with the Als3p and enolase present in the Candida albicans cell wall and exerts three anti-Candida activities: candidacidal activity and inhibition of both adhesion and filamentation. To investigate the mode of action of MAb C7 on fungal viability, we examined changes in the genome-wide gene expression profile of C. albicans grown i...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2007
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01840-06